{"product_id":"semaglutide-5mg","title":"Semaglutide 5mg","description":"\u003cp\u003e\u003cstrong\u003eBuy high-purity Semaglutide 5mg in Australia. Third-party lab tested at \u0026gt;99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhat is Semaglutide?\u003c\/strong\u003e Semaglutide is a synthetic long-acting agonist of the GLP-1 receptor — a 31-amino-acid analogue of human GLP-1 modified to extend its half-life. In published research it is studied for GLP-1 receptor signalling, glycaemic control and body composition. Optic Labs supplies HPLC-tested Semaglutide (\u0026gt;99% purity) as a lyophilised 5mg powder vial for laboratory research use only, dispatched Australia-wide from Sydney.\u003c\/p\u003e\n\n\u003ch2\u003eAbout Semaglutide\u003c\/h2\u003e\n\u003cp\u003eSemaglutide is a synthetic 31-amino-acid peptide developed by Novo Nordisk as a long-acting agonist of the glucagon-like peptide-1 receptor (GLP-1R). Structurally, it is an analogue of native human GLP-1(7–37) with substitutions at positions 8 and 34 and a fatty-acid side-chain attached via a linker at position 26 — modifications that extend its half-life relative to native GLP-1. Optic Labs supplies semaglutide as a high-purity lyophilised powder in 5mg vials, packaged for in vitro and preclinical laboratory research.\u003c\/p\u003e\n\n\u003cp\u003eEach batch is independently HPLC-tested for purity and identity, with certificates of analysis available on request.\u003c\/p\u003e\n\n\u003cp\u003eSemaglutide is one of the most extensively studied compounds in modern metabolic research, with published Phase 3 clinical trial data examining glycaemic control and body composition across multiple programmes. Optic Labs supplies semaglutide for laboratory research only — not for human consumption, clinical use, or any therapeutic application.\u003c\/p\u003e\n\n\u003ch2\u003eProduct specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e Semaglutide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 910463-68-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e 31 amino acids (modified GLP-1[7–37] analogue with C18 fatty-acid side chain)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C\u003csub\u003e187\u003c\/sub\u003eH\u003csub\u003e291\u003c\/sub\u003eN\u003csub\u003e45\u003c\/sub\u003eO\u003csub\u003e59\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e ~4113.6 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism (research context):\u003c\/strong\u003e Single agonist — GLP-1R\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised (freeze-dried) white powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% by HPLC\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable size:\u003c\/strong\u003e 5mg vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store unreconstituted vials at 2–8°C; protect from light. Reconstituted solution stored at 2–8°C and used within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Manufactured to research-grade specifications, third-party HPLC verified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Australia-wide domestic dispatch from Sydney, NSW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch background\u003c\/h2\u003e\n\u003cp\u003eSemaglutide was developed as a long-acting GLP-1 receptor agonist following earlier short-acting GLP-1 analogues. Published preclinical and clinical research has examined semaglutide in the context of:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGLP-1 receptor binding, signalling and downstream pathways\u003c\/li\u003e\n\u003cli\u003eGlycaemic control and insulin sensitivity in type 2 diabetes research models\u003c\/li\u003e\n\u003cli\u003eBody composition and adiposity in animal models and clinical study populations\u003c\/li\u003e\n\u003cli\u003eGastric emptying and appetite-regulation research\u003c\/li\u003e\n\u003cli\u003eCardiovascular outcomes research in clinical study programmes (SUSTAIN, SELECT)\u003c\/li\u003e\n\u003cli\u003ePhase 1, 2 and 3 clinical pharmacokinetic, glycaemic and weight-change studies (SUSTAIN, STEP programmes)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eReconstitution and handling\u003c\/h2\u003e\n\u003cp\u003eSemaglutide is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use in any laboratory protocol. A 5mg vial reconstituted in 1mL of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e yields a working concentration of 5mg\/mL; 2mL yields 2.5mg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eExact volumes should be calculated for each protocol — our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e walks through the maths. Reconstituted vials should be stored refrigerated at 2–8°C and protected from light.\u003c\/p\u003e\n\n\u003ch2\u003eComparisons and related research compounds\u003c\/h2\u003e\n\u003cp\u003eSemaglutide sits within the broader class of incretin and metabolic peptides. Researchers may also be interested in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/tirzepatide-10mg\"\u003eTirzepatide\u003c\/a\u003e — dual GLP-1 + GIP agonist, second-generation incretin research compound\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/retatrutide-5mg-10mg-15mg-20mg-30mg-60mg\"\u003eRetatrutide\u003c\/a\u003e — triple agonist (GLP-1 + GIP + glucagon), third-generation incretin research compound\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/aod-9604-5mg\"\u003eAOD-9604\u003c\/a\u003e — fragment growth-hormone analogue, fat-loss research\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/tesamorelin-10mg\"\u003eTesamorelin\u003c\/a\u003e — GHRH analogue, lipolysis research\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/5-amino-1mq-10mg\"\u003e5-Amino-1MQ\u003c\/a\u003e — NNMT inhibitor, metabolic research\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\n\u003ch3\u003eIs semaglutide legal in Australia?\u003c\/h3\u003e\n\u003cp\u003eSemaglutide is registered with the Therapeutic Goods Administration (TGA) as a Schedule 4 prescription-only therapeutic medicine in Australia under separate brand registrations. Optic Labs does not supply semaglutide as a therapeutic, prescription or compounded product, and semaglutide from Optic Labs is not intended for personal, clinical or therapeutic use. Optic Labs supplies semaglutide strictly as a research-grade material for in vitro and preclinical laboratory research only. For a detailed overview of peptide legality in Australia, see our \u003ca href=\"\/blogs\/news\/are-peptides-legal-australia-tga-compliance-2025\"\u003eguide to peptide legality and TGA compliance in Australia\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhat is semaglutide?\u003c\/h3\u003e\n\u003cp\u003eSemaglutide is a synthetic GLP-1 receptor agonist — a 31-amino-acid peptide modified from native human GLP-1 with substitutions and a fatty-acid side chain that extend its half-life. In published research it has been investigated for its effects on glycaemic control, body composition, hepatic lipid metabolism, gastric emptying and cardiovascular endpoints.\u003c\/p\u003e\n\n\u003ch3\u003eHow does semaglutide differ from tirzepatide and retatrutide?\u003c\/h3\u003e\n\u003cp\u003eSemaglutide is a single GLP-1 receptor agonist. \u003ca href=\"\/products\/tirzepatide-10mg\"\u003eTirzepatide\u003c\/a\u003e is a dual GLP-1 + GIP agonist. \u003ca href=\"\/products\/retatrutide-5mg-10mg-15mg-20mg-30mg-60mg\"\u003eRetatrutide\u003c\/a\u003e adds a third receptor target — the glucagon receptor — making it a triple agonist. The published research literature has examined each compound across its own clinical programme, and the receptor profiles differ in mechanism rather than being directly interchangeable.\u003c\/p\u003e\n\n\u003ch3\u003eHow is semaglutide supplied?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs supplies semaglutide as a lyophilised powder in a sealed glass research vial at the 5mg size. Each vial is shipped with a tamper-evident seal. Certificates of analysis showing HPLC purity testing are available on request.\u003c\/p\u003e\n\n\u003ch3\u003eHow much bacteriostatic water do I mix with a semaglutide 5mg vial?\u003c\/h3\u003e\n\u003cp\u003eReconstitution volume depends on the working concentration required by the research protocol. As a starting reference: 5mg in 1mL of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e yields 5mg\/mL; 5mg in 2mL yields 2.5mg\/mL. Our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution guide\u003c\/a\u003e covers the calculations.\u003c\/p\u003e\n\n\u003ch3\u003eHow should reconstituted semaglutide be stored?\u003c\/h3\u003e\n\u003cp\u003eUnreconstituted vials should be stored at 2–8°C and protected from light. Once reconstituted, the solution should be refrigerated at 2–8°C and used within approximately 30 days. For full storage protocols, see our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhere does Optic Labs ship to?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.\u003c\/p\u003e\n\n\u003ch2\u003eLegal disclaimer\u003c\/h2\u003e\n\u003cp\u003eAll products on this site are supplied for \u003cstrong\u003elaboratory research, development or analytical use only\u003c\/strong\u003e. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the \u003cstrong\u003eTherapeutic Goods Administration (TGA)\u003c\/strong\u003e or the \u003cstrong\u003eAPVMA\u003c\/strong\u003e and are not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\n\u003cp\u003eOptic Labs is not a \u003cstrong\u003ecompounding pharmacy\u003c\/strong\u003e or manufacturing facility as defined under the \u003cem\u003eTherapeutic Goods Act 1989\u003c\/em\u003e, and is not a registered provider of scheduled medicines or therapeutic goods.\u003c\/p\u003e","brand":"Optic Labs","offers":[{"title":"Default Title","offer_id":51430827393249,"sku":null,"price":79.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0867\/4076\/2849\/files\/hf_20260522_095136_47fe6b0b-7757-49de-9a4a-7d86258dba82.png?v=1794295892","url":"https:\/\/opticlabsaus.com\/products\/semaglutide-5mg","provider":"Optic Labs","version":"1.0","type":"link"}