Semaglutide 5mg

Buy high-purity Semaglutide 5mg in Australia. Third-party lab tested at >99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.

What is Semaglutide? Semaglutide is a synthetic long-acting agonist of the GLP-1 receptor — a 31-amino-acid analogue of human GLP-1 modified to extend its half-life. In published research it is studied for GLP-1 receptor signalling, glycaemic control and body composition. Optic Labs supplies HPLC-tested Semaglutide (>99% purity) as a lyophilised 5mg powder vial for laboratory research use only, dispatched Australia-wide from Sydney.

About Semaglutide

Semaglutide is a synthetic 31-amino-acid peptide developed by Novo Nordisk as a long-acting agonist of the glucagon-like peptide-1 receptor (GLP-1R). Structurally, it is an analogue of native human GLP-1(7–37) with substitutions at positions 8 and 34 and a fatty-acid side-chain attached via a linker at position 26 — modifications that extend its half-life relative to native GLP-1. Optic Labs supplies semaglutide as a high-purity lyophilised powder in 5mg vials, packaged for in vitro and preclinical laboratory research.

Each batch is independently HPLC-tested for purity and identity, with certificates of analysis available on request.

Semaglutide is one of the most extensively studied compounds in modern metabolic research, with published Phase 3 clinical trial data examining glycaemic control and body composition across multiple programmes. Optic Labs supplies semaglutide for laboratory research only — not for human consumption, clinical use, or any therapeutic application.

Product specifications

• Compound: Semaglutide
• CAS number: 910463-68-2
• Sequence: 31 amino acids (modified GLP-1[7–37] analogue with C18 fatty-acid side chain)
• Molecular formula: C₁₈₇H₂₉₁N₄₅O₅₉
• Molecular weight: ~4113.6 g/mol
• Mechanism (research context): Single agonist — GLP-1R
• Form: Lyophilised (freeze-dried) white powder
• Purity: >99% by HPLC
• Available size: 5mg vial
• Storage: Store unreconstituted vials at 2–8°C; protect from light. Reconstituted solution stored at 2–8°C and used within 30 days.
• Origin: Manufactured to research-grade specifications, third-party HPLC verified
• Shipping: Australia-wide domestic dispatch from Sydney, NSW

Research background

Semaglutide was developed as a long-acting GLP-1 receptor agonist following earlier short-acting GLP-1 analogues. Published preclinical and clinical research has examined semaglutide in the context of:

• GLP-1 receptor binding, signalling and downstream pathways
• Glycaemic control and insulin sensitivity in type 2 diabetes research models
• Body composition and adiposity in animal models and clinical study populations
• Gastric emptying and appetite-regulation research
• Cardiovascular outcomes research in clinical study programmes (SUSTAIN, SELECT)
• Phase 1, 2 and 3 clinical pharmacokinetic, glycaemic and weight-change studies (SUSTAIN, STEP programmes)

Reconstitution and handling

Semaglutide is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use in any laboratory protocol. A 5mg vial reconstituted in 1mL of bacteriostatic water yields a working concentration of 5mg/mL; 2mL yields 2.5mg/mL.

Exact volumes should be calculated for each protocol — our reconstitution calculator guide walks through the maths. Reconstituted vials should be stored refrigerated at 2–8°C and protected from light.

Comparisons and related research compounds

Semaglutide sits within the broader class of incretin and metabolic peptides. Researchers may also be interested in:

• Tirzepatide — dual GLP-1 + GIP agonist, second-generation incretin research compound
• Retatrutide — triple agonist (GLP-1 + GIP + glucagon), third-generation incretin research compound
• AOD-9604 — fragment growth-hormone analogue, fat-loss research
• Tesamorelin — GHRH analogue, lipolysis research
• 5-Amino-1MQ — NNMT inhibitor, metabolic research

Frequently asked questions

Is semaglutide legal in Australia?

Semaglutide is registered with the Therapeutic Goods Administration (TGA) as a Schedule 4 prescription-only therapeutic medicine in Australia under separate brand registrations. Optic Labs does not supply semaglutide as a therapeutic, prescription or compounded product, and semaglutide from Optic Labs is not intended for personal, clinical or therapeutic use. Optic Labs supplies semaglutide strictly as a research-grade material for in vitro and preclinical laboratory research only. For a detailed overview of peptide legality in Australia, see our guide to peptide legality and TGA compliance in Australia.

What is semaglutide?

Semaglutide is a synthetic GLP-1 receptor agonist — a 31-amino-acid peptide modified from native human GLP-1 with substitutions and a fatty-acid side chain that extend its half-life. In published research it has been investigated for its effects on glycaemic control, body composition, hepatic lipid metabolism, gastric emptying and cardiovascular endpoints.

How does semaglutide differ from tirzepatide and retatrutide?

Semaglutide is a single GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 + GIP agonist. Retatrutide adds a third receptor target — the glucagon receptor — making it a triple agonist. The published research literature has examined each compound across its own clinical programme, and the receptor profiles differ in mechanism rather than being directly interchangeable.

How is semaglutide supplied?

Optic Labs supplies semaglutide as a lyophilised powder in a sealed glass research vial at the 5mg size. Each vial is shipped with a tamper-evident seal. Certificates of analysis showing HPLC purity testing are available on request.

How much bacteriostatic water do I mix with a semaglutide 5mg vial?

Reconstitution volume depends on the working concentration required by the research protocol. As a starting reference: 5mg in 1mL of bacteriostatic water yields 5mg/mL; 5mg in 2mL yields 2.5mg/mL. Our reconstitution guide covers the calculations.

How should reconstituted semaglutide be stored?

Unreconstituted vials should be stored at 2–8°C and protected from light. Once reconstituted, the solution should be refrigerated at 2–8°C and used within approximately 30 days. For full storage protocols, see our peptide storage guide.

Where does Optic Labs ship to?

Optic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.

Legal disclaimer

All products on this site are supplied for laboratory research, development or analytical use only. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the Therapeutic Goods Administration (TGA) or the APVMA and are not intended to diagnose, treat, cure or prevent any disease.

Optic Labs is not a compounding pharmacy or manufacturing facility as defined under the Therapeutic Goods Act 1989, and is not a registered provider of scheduled medicines or therapeutic goods.